Transforming growth factor beta1 is expressed in the jejunum after experimental Cryptosporidium parvum infection in humans.
نویسندگان
چکیده
Biopsies from volunteers challenged with Cryptosporidium parvum were examined for transforming growth factor beta1 (TGF-beta1). None of the prechallenge biopsies exhibited TGF-beta. Seven of 12 volunteers with oocyst shedding expressed TGF-beta versus 2 of 13 volunteers without detected oocysts. The association of TGF-beta expression with oocyst excretion and the timing of symptoms suggests that TGF-beta mediates intestinal healing.
منابع مشابه
Transforming Growth Factor b1 Is Expressed in the Jejunum after Experimental Cryptosporidium parvum Infection in Humans
Biopsies from volunteers challenged with Cryptosporidium parvum were examined for transforming growth factor b1 (TGF-b1). None of the prechallenge biopsies exhibited TGF-b. Seven of 12 volunteers with oocyst shedding expressed TGF-b versus 2 of 13 volunteers without detected oocysts. The association of TGF-b expression with oocyst excretion and the timing of symptoms suggests that TGF-b mediate...
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ورودعنوان ژورنال:
- Infection and immunity
دوره 68 9 شماره
صفحات -
تاریخ انتشار 2000